Priv.-Doz. Dr. med. Henning Stubbe
Chefarzt der Abteilung für Anästhesie, Intensivmedizin und Schmerztherapie , Niels-Stensen-Kliniken, Marienhospital Osnabrück - Standort Natruper Holz
Facharzt für Anästhesie und Intensivmedizin, Notfallmedizin und Spezielle Schmerztherapie
Ärztlicher Direktor des Marienhospitals Osnabrück - Standort Natruper Holz
Lebenslauf
Beruflicher Werdegang
| Studium 1993-2000: Westfälische Wilhelms-Universität Münster und University of Natal, Durban, Südafrika |
| Promotion: "Die Entwicklung des extravaskulären Lungenwassers unter NO-Synthase-Inhibition und NO-Inhalation in der hyperdynamen Endotoxinämie im Schaf" Münster, 2001 |
| Habilitation: "Experimentelle Untersuchungen zur zerebralen und pulmonalen Gefäßregulation und Flüssigkeitsfiltration in der Sepsis – Bedeutung für Prophylaxe und Therapie des Multiorganversagens" Münster, 2008 |
Berufliche Tätigkeiten
| 2018: Weiterbildung Spezielle Schmerztherapie |
| 2015: Ärztlicher Direktor Marienhospital Osnabrück - Standort Natruper Holz |
Veröffentlichungen
Ridwan S, Ostertun B, Stubbe H, Hans F-J. First report of extraspinal lead migration along a spinal thoracic nerveafter spinal cord stimulation. World Neurosurg 2020 Sept; 141:257-250.
Sommer B, Karageorgos N, AlSharif M, Stubbe H, Hans FJ. Long-term Outcome and Adverse Events of Intrathecal Opioid Therapy for Nonmalignant Pain Syndrome. Pain Pract. 2020 Jan;20(1):8-15.
Stubbe HD. Salt or sugar on the brain: does it matter except for taste? Crit Care Med. 2011 Mar;39(3):601-2.
Ellger B, Westphal M, Stubbe HD, Van den Heuvel I, Van Aken H, Van den Berghe G. Blutzuckerkontrolle bei Patienten mit Sepsis und septischem Schock: Freund oder Feind? [Glycemic control in sepsis and septic shock: friend or foe?]. Anaesthesist. 2008 Jan;57(1):43-8. German.
Lauer S, Fischer LG, Stubbe HD, Van Aken H, Westphal M. (K)eine Surfactant- Therapie bei Patienten mit "acute respiratory distress syndrome"?: Bedeutung einer Surfactant-Substitutionstherapie in der Behandlung des akuten Lungenversagens [Value of surfactant replacement therapy in the treatment of acute respiratory distress syndrome]. Anaesthesist. 2006 Apr;55(4):433-42.
Westphal M, Sander J, Van Aken H, Ertmer C, Stubbe HD, Booke M. Bedeutung von Adrenomedullin Pathogenese und Behandlung kardiovaskulärer Dysfunktionen der Sepsis [Role of adrenomedullin in the pathogenesis and treatment of cardiovascular dysfunctions and sepsis]. Anaesthesist. 2006 Feb;55(2):171-8. German.
Eletr D, Reich A, Stubbe HD, Booke M, Daudel F, Erren M, Westphal M. Arteriovenous carboxyhemoglobin difference is not correlated to TNF-alpha, IL-6, PCT, CRP and leukocytes in critically ill patients. Clin Chim Acta. 2004 Nov;349(1-2):75-80. doi: 10.1016/j.cccn.2004.06.005. PMID: 15469858.
Daudel F, Bone HG, Traber DL, Stubbe HD, Lettau M, Lange M, Scharte M, Van Aken H, Westphal M. Effects of thoracic epidural anesthesia on hemodynamics and global oxygen transport in ovine endotoxemia. Shock. 2006 Dec;26(6):615-9.
Daudel F, Freise H, Westphal M, Stubbe HD, Lauer S, Bone HG, Van Aken H, Sielenkämper AW. Continuous thoracic epidural anesthesia improves gut mucosal microcirculation in rats with sepsis. Shock. 2007 Nov;28(5):610-4.
Stubbe H, Schmidt C, Hinder F. Invasives Kreislaufmonitoring--Vier Methoden im Vergleich [Invasive cardiovascular monitoring--four methods compared]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2006 Sep;41(9):550-5. German.
Stubbe HD, Greiner C, Van Aken H, Rickert CH, Westphal M, Wassmann H, Akcocuk A, Daudel F, Erren M, Hinder F. Cerebral vascular and metabolic response to sustained systemic inflammation in ovine traumatic brain injury. J Cereb Blood Flow Metab. 2004 Dec;24(12):1400-8.
Stubbe HD, Traber DL, Booke M, Traber LD, Westphal M, Van Aken H, Hinder F. Role of atrial natriuretic peptide in pulmonary permeability and vasoregulation in ovine sepsis. Crit Care Med. 2004 Dec;32(12):2491-5.
Hinder F, Stubbe HD, Van Aken H, Baba HA, Jahn UR, Brodner G, August C, Erren M, Booke M. Early multiple organ failure after recurrent endotoxemia in the presence of vasoconstrictor-masked hypovolemia. Crit Care Med. 2003 Mar;31(3):903-9.
Baba HA, Wohlschlaeger J, Stubbe HD, Grabellus F, Aken HV, Schmitz KJ, Otterbach F, Schmid KW, August C, Levkau B, Hinder F. Heat shock protein 72 and apoptosis indicate cardiac decompensation during early multiple organ failure in sheep. Intensive Care Med. 2004 Jul;30(7):1405-13.
Wohlschlaeger J, Stubbe HD, Schmitz KJ, Kawaguchi N, Takeda A, Takeda N, Hinder F, Baba HA. Roles of MMP-2/-9 in cardiac dysfunction during early multiple organ failure in an ovine animal model. Pathol Res Pract. 2005;201(12):809-17.
Stubbe HD, Greiner C, Westphal M, Rickert CH, Aken HV, Eichel V, Wassmann H, Daudel F, Hinder F. Cerebral response to norepinephrine compared with fluid resuscitation in ovine traumatic brain injury and systemic inflammation. Crit Care Med. 2006 Oct;34(10):2651-7.
Lauer S, Daudel F, Traber DL, Nofer JR, Ertmer C, Morelli A, Van Aken H, Lange M, Rehberg S, Ellger B, Stubbe HD, Kruse C, Bone HG, Westphal M. Somatostatin infusion increases intestinal ischemia and does not improve vasoconstrictor response to norepinephrine in ovine endotoxemia. Shock. 2008 Nov;30(5):603-9.
Hinder F, Stubbe HD, Van Aken H, Waurick R, Booke M, Meyer J. Role of nitric oxide in sepsis-associated pulmonary edema. Am J Respir Crit Care Med. 1999 Jan;159(1):252-7.
Daudel F, Ertmer C, Stubbe HD, Lange M, Pulina R, Bone HG, Sielenkämper AW, Van Aken H, Westphal M. Hemodynamic effects of thoracic epidural analgesia in ovine hyperdynamic endotoxemia. Reg Anesth Pain Med. 2007 Jul-Aug;32(4):311-6.
Lange M, Williams W, Bone HG, Van Aken H, Bröking K, Morelli A, Hucklenbruch C, Daudel F, Ertmer C, Stubbe H, Traber DL, Westphal M. Continuously infused glipizide reverses the hyperdynamic circulation in ovine endotoxemia. Shock. 2007 Jun;27(6):701-6.
Stubbe HD, Westphal M, Van Aken H, Hucklenbruch C, Lauer S, Jahn UR, Hinder F. Inhaled nitric oxide reduces lung edema during fluid resuscitation in ovine acute lung injury. Intensive Care Med. 2003 Oct;29(10):1790-7.
Ertmer C, Morelli A, Bone HG, Stubbe HD, Schepers R, Van Aken H, Lange M, Bröking K, Lücke M, Traber DL, Westphal M. Dobutamine reverses the vasopressin- associated impairment in cardiac index and systemic oxygen supply in ovine endotoxemia. Crit Care. 2006;10(5):R144.
Westphal M, Sielenkämper AW, Van Aken H, Stubbe HD, Daudel F, Schepers R, Schulte S, Bone HG. Dopexamine reverses the vasopressin-associated impairment in tissue oxygen supply but decreases systemic blood pressure in ovine endotoxemia. Anesth Analg. 2004 Sep;99(3):878-85, table of contents.
Westphal M, Daudel F, Bone HG, Van Aken H, Sander J, Stubbe H, Booke M. New approach to an ovine model of hypodynamic endotoxaemia. Eur J Anaesthesiol. 2004 Aug;21(8):625-31.
Westphal M, Stubbe H, Sielenkämper AW, Borgulya R, Van Aken H, Ball C, Bone HG. Terlipressin dose response in healthy and endotoxemic sheep: impact on cardiopulmonary performance and global oxygen transport. Intensive Care Med. 2003 Feb;29(2):301-8.
Westphal M, Stubbe H, Bone HG, Daudel F, Vocke S, Van Aken H, Booke M. Hemodynamic effects of exogenous adrenomedullin in healthy and endotoxemic sheep. Biochem Biophys Res Commun. 2002 Aug 9;296(1):134-8.